Chinese Peptide Company


[Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human
Size : 0.25
P1(RMB) : 529
MW : 3481
One letter sequence : Biotin-KGGHLKSK-K(Ac)-GQSTSRHKKLMFKTEGPDSD-NH2
Molecular Formula :
Description : This peptide is tumor suppressor protein, p53 (368-393). There is a biotinylated lyine followed by a GG linker at the N-terminal and an acetylated lysine at lysine 373. Activation of the p53 protein results in the transcription of antiproliferative proteins and induction of apoptosis. The p53 tumor suppressor is a principal mediator of growth arrest, senescence, and apoptosis in response to a broad array of cellular damage.
Literature Reference : Kanovsky, M. et al. Proc Natl Acad Sci 98, 12438 (2001).
Cas :