Chinese Peptide Company


H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH Trifluoroacetate salt
Size : 1
P1(RMB) : 262
MW : 1739.95
One letter sequence : SFLLRNPNDKYEPF
Molecular Formula : C81H118N20O23
Description : This peptide is a 14-amino acid peptide mimicking the potent thrombin receptor activator as well as an effective agonist for platelet activation. This peptide is the fragment 42-55 of the human thrombin receptor and fully reproduces the action of thrombin on MMPs in vascular endothelial cells. This peptide (TRP-14) may signal a variety of thrombin’s responses and has been shown to cause platelet aggregation that can evoke a wide range of G-protein dependent responses.
Literature Reference : T.-K.H.Vu et al., Cell, 64, 1057 (1991) Y.Maruyama et al., Biochem. Biophys. Res. Commun., 199, 1262 (1994) Duhamel-Clérin, E. et al. Arterioscler. Thromb. Vasc. Biol. 17, 1931 (1997); Vassallo, R. et al. J. Biol. Chem. 267, 6081 (1992); Y. Sugama and AB. Malik. Circ. Res. 71, 1015 (1992).
Cas : 137339-65-2