Chinese Peptide Company


PAR-4 (1-6) (human)
H-Gly-Tyr-Pro-Gly-Gln-Val-OH Trifluoroacetate salt
Size : 25
P1(RMB) : 1208
MW : 619.68
One letter sequence : GYPGQV
Molecular Formula : C28H41N7O9
Description : This peptide is the amino terminus of the fourth protease-activated receptor (PAR4) after the cleavage at Arg47/Gly48 was tested for its ability to stimulate COS cells expressing PAR4. The peptide readily activated both wild-type and mutant PAR4 (R47A) at 500 µM, whereas thrombin and trypsin only activate the wild-type PAR4.
Literature Reference : W.-F.Xu et al., Proc. Natl. Acad. Sci. USA, 95, 6642 (1998) H.Andersen et al., Proc. Natl. Acad. Sci. USA, 96, 11189 (1999) R.Kaufmann et al., J. Cancer Res. Clin. Oncol., 126, 91 (2000)
Cas : 225779-44-2