Chinese Peptide Company


PAR-2 (1-6) (mouse, rat)
Ser-Leu-Ile-Gly-Arg-Leu-OH Trifluoroacetate salt
Size : 5
P1(RMB) : 671
MW : 657.81
One letter sequence : SLIGRL
Molecular Formula : C29H55N9O8
Description : This peptide is the tethered ligand sequence of mouse PAR-2, which like the thrombin receptor is a protease-activated receptor present in keratinocytes. This peptide was found to be equipotent with SFLLRN in activating keratinocyte inositolphospholipid hydrolysis and calcium mobilization.
Literature Reference : R.J.Santulli et al., Proc. Natl. Acad. Sci. USA, 92, 9151 (1995) A. Bhattacharya et al., J. Pharmacol. Exp. Ther., 297, 573 (2001). B. Al-Ani, et al., J. of Physiol. Pharmacol., 73, 1203 (1995).
Cas : 164081-25-8