Chinese Peptide Company


IGF-I Analog
Cys-Tyr-Ala-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Cys (Disulfide bond)
Size : 5
P1(RMB) : 2400
MW : 1249.52
One letter sequence : CYAAPLKPAKSC
Molecular Formula : C55H88N14O15S2
Description : This IGF-I peptide analog was able to inhibit the autophosphorylation of the IGF-I receptor by IGF-I as well as the growth of several different cell types, including prostate carcinoma cells and SV40-transformed cells. Such analogs might be useful in treating abnormal cell growth.
Literature Reference : Z.Pietrzkowski et al., Cancer Res., 52, 6447 (1992)Z.Pietrzkowski et al., Cancer Res., 53, 1102 (1993)G.Camarero et al., Dev. Biol., 262, 242 (2003)L.Croci et al., Cell Death Differ., 18, 48 (2011)
Cas : 147819-32-7