Size : 0.5
P1(RMB) : 632
MW : 2643.04
One letter sequence : LFTMTGLKRDKTKEYNETWYC
Molecular Formula : C118H180N30O35S2
Description : Two monoclonal antibodies (MAbs), reactive with the external envelope glycoprotein of the simian immunodeficiency virus of macaque monkey and displaying a cellfree virus-neutralizing activity, were generated. Epitope mapping of these MAbs permitted to delineate a neutralizing domain localized in the second variable region of the SIVmac251 gp105, between amino acids 171 and 188. This domain is enclosed in the above sequence. In addition, this neutralizing domain usually induces a specific humoral response in experimentally SIVmac-infected macaques.
Literature Reference : K.A.Kent et al., AIDS, 5, 829 (1991)