Size : 1
P1(RMB) : 306
MW : 1164.2
One letter sequence : GRPRTSSFAEG
Molecular Formula : C48H77N17O17
Description : Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB and displays similar specificities towards PKBalpha, PKBbeta and PKBgamma isoforms. It is also recognized by MAPKAP kinase-1 and p70S6K. The fluorescent and biotinlyated peptides demonstrate similar enzyme activities.
Literature Reference : Dai, F. et al. Biochem. Biophys. Res. Commun. 293, 1191 (2002)Meier, R. et al. J. Biol. Chem. 272, 30491 (1997)Chan, TO. et al. Ann. Rev. Biochem. 68, 965 (1999).