Size : 1
P1(RMB) : 398
MW : 1942.3
One letter sequence : LQNRRGLDLLFLKEGGL
Molecular Formula : C87H148N26O24
Description : Peptide isolated from a highly conserved region of the immunosuppressive retroviral envelope protein p15E that is also capable of inhibiting lymphocyte proliferation, B cell activation, natural killer cell cytotoxicity, and monocyte-mediated tumor cytotoxicity. It has been found that CKS-17 leads to the rise of intracellular cAMP levels that may affect on several physiological cellular funtions.
Literature Reference : R. A. J. Oostendorp et al., Eur. J. Immunol., 22, 1505 (1992)