Size : 1
P1(RMB) : 306
MW : 654.72
One letter sequence : Ac-YVAD-2,6- diMhylbenzoyloxyMhylketone
Molecular Formula : C33H42N4O10
Description : Highly selective, competitive and irreversible inhibitor of caspase-1 (ICE). Inactivation of the enzyme occurs with a rate limited by diffusion and is relatively inert toward other bionucleophiles such as glutathione, thus making it an excellent candidate for in vivo studies of enzyme inhibitors.
Literature Reference : N.A. Thornberry et al., Biochemistry, 33, 3934 (1994)
Cas : [154674-81-4]