Chinese Peptide Company


Guanylin, rat, mouse
Pro-Asn-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys(Cys4&Cys12 bridge , Cys7&Cys15 bridge)
Size : 1
P1(RMB) : 1195
MW : 1515.7
One letter sequence : PNTCEICAYAACTGC (C4&C12 bridge , C7&C15 bridge)
Molecular Formula : C60H90N16O22S4
Description : This peptide activates the guanylate cyclase in the intestine and stimulates the production of cGMP that results in a secretory diarrhoea, thereby playing a role in regulating fluid and electrolyte absorption in intestines.
Literature Reference : R.C. Wiegand et al., BBRC, 185, 812 (1992)
Cas :