Chinese Peptide Company


Mast Cell Degranulating Peptide
Ile-Lys-Cys-Asn-Cys-Lys-Arg-His-Val-Ile-Lys-Pro-His-Ile-Cys-Arg-Lys-Ile-Cys-Gly-Lys-Asn-NH2(Cys3&Cys15 bridge , Cys5&Cys19 bridge)
Size : 1
P1(RMB) : 1011
MW : 2587.3
One letter sequence : IKCNCKRHVIKPHICRKICGKN-NH2 (C3&C15 bridge , C5&C19 bridge)
Molecular Formula : C110H192N40O24S4
Description : Highly basic MCD peptide is isolated from the venom of European honeybee, Apis Mellifera. At low doses, it leads to mast cell degranulation and subsequence histamine release. At higher doses, it causes an anti-inflammatory effect, beneficial in rheumatic and allergic diseases.
Literature Reference : M.E.J. Billingham et al., Nature, 245, 163 (1973)
Cas :