Chinese Peptide Company


Vasoactive Intestinal Contractor [VIC]
Cys-Ser-Cys-Asn-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp(Cys1&Cys15 bridge , Cys3&Cys11 bridge)
Size : 0.5
P1(RMB) : 1073
MW : 2574
One letter sequence : CSCNSWLDKECVYFCHLDIIW (C1&C15 bridge , C3&C11 bridge)
Molecular Formula : C116H161N27O32S4
Description : Gastrointestinal hormone and a member of the endothelin family that exerts a direct effect on the pituitary and increases pulmonary arterial pressure. This peptide also displays a higher contractor activity on mouse and guinea pig, whereas it is weaker in its vasoconstrictor activity.
Literature Reference : N. Ishida et al., FEBS Letters, 247, 337 (1989); K. Saida et al., J. Biol. Chem., 264, 14613 (1989); M.S. Simonson et al., FASEB J., 4, 2989 (1990)
Cas :