Chinese Peptide Company


Substance P
Size : 5
P1(RMB) : 276
MW : 1347.7
One letter sequence : RPKPQQFFGLM-NH2
Molecular Formula : C63H98N18O13S1
Description : This neuropeptide was found in the gut as well as in the brain. It is responsible for a number of excitatory effects on both central and peripheral neurons. It contracts smooth muscle, constricts bronchioles and increases capillary permeability. When released from afferent nerves, it causes a neurogenic inflammatory response, including mast cell degranulation.
Literature Reference : A.I. Roberts et al., Cell Immunol., 141, 457 (1992)
Cas :